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细胞生物学iBiology

3.1万

31

2020-02-20 12:57:16

iBiology上的细胞生物学课程。

生物dalao 发消息

专于生物，精于科研，忙于实验，闲于搬运。

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1.origins of life

54:41

Jack Szostak (HarvardHHMI) Part 2 Protocell Membranes

40:44

Jack Szostak (HarvardHHMI) Part 3 Non-enzymatic Copying of Nucleic Acid Template

53:52

2.organization of cytoplasm

27:58

3.GTP-binding Proteins as Molecular Switches

42:02

4.GTPase Reactions and Diseases

55:03

5.Studying Protein Secretion in Yeast

36:36

6.Biochemical Reconstitution of Transport Vesicle Budding

25:15

7.Cell Motility

44:11

8.Molecular Motor Proteins

35:26

9.The Mechanisms of Dynein Motility

39:37

Ron Vale (UCSF, HHMI) 3 Molecular Motor Proteins Regulation of Mammalian Dynein

24:40

10.Separating Duplicated Chromosomes

29:34

11.Understanding Mitosis through Experimentation

39:03

12.Moving Chromosome to the Spindle Poles

41:28

13.Protein Phosphorylation in Biology

23:07

14.Architecture of a Protein Kinase

28:18

Mary Beckerle (University of Utah) Part 1 Adhesion, Signaling and Cancer

36:04

15.Controlling the Cell Cycle Introduction

28:32

16.Cdk Substrates

30:08

David O. Morgan (UCSF) Part 3 Controlling the Cell Cycle Anaphase Onset

21:20

Elizabeth Blackburn (UCSF) Part 1 The Roles of Telomeres and Telomerase

48:28

Elizabeth Blackburn (UCSF) Part 2 Telomeres and Telomerase in Human Stem Cells a

26:58

Elizabeth Blackburn (UCSF) Part 3 Stress, Telomeres and Telomerase in Humans

45:58

Jared Rutter (U. Utah, HHMI) 1 Mitochondria The Mysterious Cellular Parasite

30:59

Jared Rutter (U. Utah, HHMI) 2 Mitochondrial Metabolism and Cell Decisions

25:10

Jared Rutter (U. Utah, HHMI) 3 Mitochondria The Fuel and the Fire

26:09

Randy Schekman (HHMI & UCB) 1 Secretory Pathway How cells package & traffic prot

35:01

Randy Schekman (HHMI & UCB) 2 Genes and proteins required for secretion

38:29

Randy Schekman (HHMI & UCB) 3 How human cells secrete small RNAs in extracellula

38:41

Tom Rapoport (Harvard, HHMI) 1 Organelle Biosynthesis and Protein Sorting

35:01

Tom Rapoport (Harvard, HHMI) 2 How are cellular organelles shaped

32:29

Xiaodong Wang (U Texas SouthwesternHHMI) Part 1 Introduction to Apoptosis

26:16

Xiaodong Wang (U Texas SouthwesternHHMI) Part 2 The Intrinsic Pathway of Apoptos

27:40

Xiaodong Wang (U Texas SouthwesternHHMI) Part 3 Extrinsic Pathway of Apoptosis

24:01

Manuel Leonetti (CZ Biohub) Functional Genomics Systematic Approaches for Mappin

17:21

Anne Bertolotti (MRC LMB) 1 A Historical Perspective on Protein Phosphatases

29:15

Anne Bertolotti (MRC LMB) 2 Benefits of Phosphatase Inhibition for Neurodegenera

30:13

Anne Bertolotti (MRC LMB) 3 A Platform to Identify Selective Protein Phosphatase

34:15

David Drubin (UC Berkeley) 1 Actin, endocytosis and the early days of yeast cell

25:09

David Drubin (UC Berkeley) 2 Actin dynamics and endocytosis in yeast

30:25

David Drubin (UC Berkeley) 3 Actin dynamics and endocytosis in mammalian cells

35:12

David Drubin (UC Berkeley) 4 Actin assembly in budding yeast

28:37

David Sabatini (Whitehead, MIT, HHMI) 1 Introduction to mTOR and the Regulation

34:06

David Sabatini (Whitehead, MIT, HHMI) 2 Regulation of mTORC1 by Nutrients

30:55

David Sabatini (Whitehead, MIT, HHMI) 3 Ribophagy and Nucleotide Recycling

27:17

Deshaies (Amgen) 1 A primer on the ubiquitin-proteasome system

35:08

Deshaies (Amgen) 2 Cullin-RING ubiquitin ligases structure, mechanism, and regul

40:35

Deshaies (Amgen) 3 Targeting the ubiquitin-proteasome system in cancer

41:45

Gia Voeltz (CU, HHMI) 1 Factors and Functions of Organelle Membrane Contact Site

24:33

Gia Voeltz (CU, HHMI) 2 Using BioID to Identify Membrane Contact Site Factors

23:33

Jan-Michael Peters (IMP) 1 Cohesin Roles Beyond Sister Chromatid Cohesion

33:18

Jan-Michael Peters (IMP) 2 How do Cohesin and CTCF Fold DNA in Mammalian Genomes

36:34

Mitochondria - Jodi Nunnari (UC Davis)

28:03

Norma Andrews (UMCP) 1 Mechanisms of Plasma Membrane Repair

24:42

Norma Andrews (UMCP) 2 Ca2+-Dependent Lysosomal Exocytosis Mediates Endocytosis

36:23

Ramanujan Hegde (MRC) 1 Compartmentalization of Proteins Inside Cells

43:08

Ramanujan Hegde (MRC) 2 Quality Control of Protein Localization

34:09

Ramanujan Hegde (MRC) 3 Recognition of Protein Localization Signals

46:27

James Spudich (Stanford) 1 A brief history of muscle biology 1864-1969

31:06

James Spudich (Stanford) 2 A brief history of muscle biology 1969-2017

31:32

James Spudich (Stanford) 3 Ca2+ regulation of muscle contraction

32:23

James Spudich (Stanford) 4 Myosin mutations and hypertrophic cardiomyopathy

37:56

Sue Biggins (Fred Hutchinson Cancer Research Center, HHMI) 1 Chromosome Segregat

30:45

Sue Biggins (Fred Hutchinson Cancer Research Center, HHMI) 2 Investigating Kinet

23:28

Arthur Horwich (YaleHHMI) Part 1A Chaperone-assisted protein folding

38:10

Arthur Horwich (YaleHHMI) Part 1B Chaperone-assisted protein folding

20:27

Arthur Horwich (YaleHHMI) Part 2 The role of ATP binding and hydrolysis at GroEL

17:34

Arthur Horwich (YaleHHMI) Part 3 Where are proteins folded by chaperonins

17:25

Jody Rosenblatt (HCI, U. Utah) 1 Epithelial homeostasis Cell division

25:06

Jody Rosenblatt (HCI, U. Utah) 2 Epithelial Apoptosis Death by epithelial cell e

23:57

Jody Rosenblatt (HCI, U. Utah) 3 Pathologies resulting from aberrant epithelial

25:41

Julie Theriot (Stanford, HHMI) 1 Protein Polymers, Crawling Cells and Comet Tail

28:54

Julie Theriot (Stanford, HHMI) 2 Mechanics and Dynamics of Rapid Cell Motility

37:20

Julie Theriot (Stanford, HHMI) 3 Evolution of a Dynamic Cytoskeleton

41:04

Rachel Green (Johns Hopkins U., HHMI) 1 Protein synthesis a high fidelity molecu

43:06

Rachel Green (Johns Hopkins U., HHMI) 2 Protein synthesis mRNA surveillance by t

37:19

Robert Goldman (Northwestern UMBL) Part 1 Cytoskeletal Intermediate Filaments

36:08

Robert Goldman (Northwestern UMBL) Part 2 Nuclear Lamins

42:10

Susan Lindquist (Whitehead, MIT HHMI) 1a Protein Folding in Infectious Disease

21:05

Susan Lindquist (Whitehead, MIT HHMI) 1b Protein Folding in Neurodegenerative D

26:25

Susan Lindquist (Whitehead, MIT HHMI) 2 Hsp 90 a Driver of Novelty in Evolution

58:47

Susan Lindquist (Whitehead, MIT HHMI) 3 Prions Protein Elements of Genetic Dive

47:12

Angelika Amon (MIT and HHMI) Part 1 Review of the Study of Aneuploidy

32:44

Angelika Amon (MIT and HHMI) Part 2 Effects of Aneuploidy on Cell Physiology

36:54

Angelika Amon (MIT and HHMI) Part 3 Aneuploidy Disease Implications

30:32

Martin Raff (UCL) Part 1 Regulation of Cell Size

40:57

Martin Raff (UCL) Part 2 Cell Number Control

37:15

Mary Beckerle (University of Utah) Part 2 Discovery and Characterization

50:55

Mary Beckerle (University of Utah) Part 3 Focal Adhesions as Stress Sensors

30:57

Tim Mitchison (Harvard) Part 1 Self-organization of microtubule assemblies

26:01

Tim Mitchison (Harvard) Part 2 Self-organization of meiotic spindles

41:50

Bench to Bedside Genetics of Circadian Rhythms, Part 1 - Louis Ptáček

33:31

Bench to Bedside Genetics of Circadian Rhythms, Part 2 - Ying-Hui Fu

24:23

Helen Piwnica-Worms (U. Texas) 1 A Historical Perspective on Cell Cycle Regulati

29:08

Helen Piwnica-Worms (U. Texas) 2 Translating Cell Cycle Principles to Targeted C

29:28

Robert Lefkowitz (Duke University) Part 1 Seven Transmembrane Receptors

55:15

Robert Lefkowitz (Duke University) Part 2 Beta-arrestins

51:39

Ron Vale (UCSFHHMI), Lasker Foundation, Stuyvesant High School - Molecular Motor

21:17

J. Michael Bishop (UCSF) Part 1 Forging a genetic paradigm for cancer

28:37

J. Michael Bishop (UCSF) Part 2 The cancer genome Challenge and promise

43:33

J. Michael Bishop (UCSF) Part 3 The cancer genome and therapeutics

40:55

Brian Druker (OHSU) Part 1- Imatinib (Gleevec)- A Targeted Cancer Therapy

33:55

Brian Druker (OHSU) Part 2- Imatinib Resistance and Other Diseases Targeted by I

25:13

Brian Druker (OHSU) Part 3- Extending the Imatinib Paradigm

22:10

John Schiller (NCI at NIH) 1- Human Papillomavirus (HPV) Vaccines to Prevent Can

32:44

John Schiller (NCI at NIH) 2- Why Do HPV Virus-Like Particle Vaccines Work So We

34:26

Gia Voeltz (CU, HHMI) 1- Factors and Functions of Organelle Membrane Contact Sit

24:33

Gia Voeltz (CU, HHMI) 2- Using BioID to Identify Membrane Contact Site Factors

23:33

Susan Taylor (UCSD) Part 1- Protein Phosphorylation in Biology

23:08

Susan Taylor (UCSD) Part 2- Architecture of a Protein Kinase

28:15

Susan Taylor (UCSD) Part 3 Protein Kinase Regulation and Localization

27:05

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