笑气到底有多危险？它没有针头、没有异味，甚至是能在网上买到的“奶油发泡剂”，却能造成不可逆的神经系统损伤，让人出现幻觉、大小便失禁，甚至瘫痪。从吸入第一口笑气开始，身体究竟经历了什么？解剖和病理学面前，从来没有侥幸。
参考文献：
[1]GERNEZ E, LEE G R, NIGUET J P, et al. Nitrous Oxide Abuse: Clinical Outcomes, Pharmacology, Pharmacokinetics, Toxicity and Impact on Metabolism[J]. Toxics, 2023, 11(12): 962.
[2]WONG J, VIYASAR T, LAYTON B, et al. The dangers of recreational inhalation of nitrous oxide[J]. British Journal of Hospital Medicine, 2021, 82(12): 1-8.
[3]THAYABARAN D, BURRAGE D. Nitrous oxide‐induced neurotoxicity: A case report and literature review[J]. British Journal of Clinical Pharmacology, 2021, 87(9): 3622-3626.
[4]WINSTOCK A R, FERRIS J A. Nitrous oxide causes peripheral neuropathy in a dose dependent manner among recreational users[J]. Journal of Psychopharmacology, 2019, 34(2): 229-236.
[5]EINSIEDLER M, VOULLEMINOT P, DEMUTH S, et al. A rise in cases of nitrous oxide abuse: neurological complications and biological findings[J]. Journal of Neurology, 2021, 269(2): 577-582.
[6]BRUNT T M, VAN DEN BRINK W, VAN AMSTERDAM J. Mechanisms Involved in the Neurotoxicity and Abuse Liability of Nitrous Oxide: A Narrative Review[J]. International Journal of Molecular Sciences, 2022, 23(23): 14747.
[7]WILLIAMSON J, HUDA S, DAMODARAN D. Nitrous oxide myelopathy with functional vitamin B12deficiency[J]. BMJ Case Reports, 2019, 12(2): e227439.
