[#22-05] 生医工在线学术讲座 美国弗吉尼亚大学生物医学工程系主任 Frederick H. Epstein 教授 位移编码 MRI
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2022-04-14 16:02:38
未经作者授权，禁止转载上科大生医工在线学术讲座
讲座题目：位移编码 MRI：从基本原理到临床应用与商业化
演讲人：Frederick H. Epstein 教授
美国弗吉尼亚大学 Mac Wade 冠名教授
生物医学工程系主任
工程学院副院长
讲座摘要：The use and value of quantitative tissue-motion imaging continue to increase, and methods that are accurate, reproducible, and easy to use are needed. MRI stimulated echoes have the unique property that tissue displacement can be encoded directly into the phase of the signal. We have exploited this property to develop MRI pulse sequences and image analysis methods that enable the accurate and reproducible measurement of tissue motion using protocols suitable for imaging human subjects. This seminar will review the various properties of the signals sampled when imaging using DENSE (displacement encoding using stimulated echoes), the development of DENSE pulse sequences that enable efficient and accurate imaging of the displacement-encoded signal, and the development of image analysis algorithms for quantifying displacement trajectories and tissue strain from DENSE images. In addition to describing methods for displacement-encoded MRI, this seminar will review studies by our group and others showing the application of DENSE imaging to quantify tissue motion in the heart and other organs, demonstrating the clinical and basic science utility of this method. The path to commercialization of DENSE MRI will also be discussed.
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