演讲人： Bharat B. Biswal 教授
讲座摘要：Using resting-state fMRI signals, we can map temporally synchronized brain activity across local brain regions. However, most of these studies in fMRI have primarily focused on the gray-matter BOLD signals. The signals from the white matter have usually been considered to be noise dominated and rarely reported in the literature. Recent studies have demonstrated the presence of small yet reliable changes in specific white-matter regions responding to tasks. A few studies have also demonstrated neural driven white-matter signal fluctuations during rest. We hypothesize that the corpus callosum, the largest white matter structure, maybe differentially connected with WM-FNs (White-Matter Functional Networks). To address this hypothesis, we evaluated the WM-FNs by performing a clustering analysis to the voxel-based white-matter functional connectivity matrix and studied the relationships between WM- (white matter) and GM (grey matter)-FNs. Subsequently, we used partial correlation analysis to explore the connectivity between the WM-FNs and each voxel in the corpus callosum. In this talk, I will first introduce our group’s works on FC (functional connectivity) and then the WM FC.