熊去氧胆酸（Ursodeoxycholic Acid，简称UDCA）是一种胆汁酸，自然存在于人体和某些动物的胆汁中，特别是在熊的胆汁中含量较高，因此得名。UDCA是一种重要的药物，主要用于治疗胆汁淤积性肝病，如原发性胆汁性胆管炎（PBC）和原发性硬化性胆管炎（PSC），以及溶解胆固醇性胆结石。它的作用机制包括保护肝细胞、改善胆汁流动性和降低胆固醇饱和度。

 药理作用

熊去氧胆酸通过多种机制发挥其治疗作用：

- **改善胆汁流动性**：UDCA能够增加胆汁流动，减轻胆汁淤积，从而缓解胆汁淤积性肝病的症状。

- **保护肝细胞**：UDCA能够减少对肝细胞的毒性损伤，保护肝细胞免受胆汁酸的损害。

- **降低胆固醇饱和度**：通过抑制胆固醇的合成和吸收，UDCA能够降低胆固醇在胆汁中的饱和度，有助于溶解胆固醇性胆结石。

 临床应用

- **治疗胆汁淤积性肝病**：如原发性胆汁性胆管炎（PBC）和原发性硬化性胆管炎（PSC）。

- **溶解胆固醇性胆结石**：适用于无症状的小胆固醇结石患者，特别是那些因手术风险过高或拒绝手术的患者。

- **其他应用**：包括治疗妊娠相关的胆汁淤积、胆汁返流性胃炎和某些情况下的胰腺炎。

 使用和剂量

熊去氧胆酸的剂量根据治疗的疾病、患者的体重和医生的判断来确定。通常，治疗胆固醇性胆结石的剂量范围在10-15 mg/kg/day，分两次服用，而治疗胆汁淤积性肝病的剂量可能更高。

熊去氧胆酸是一种有效的药物，用于治疗多种胆汁系统疾病，包括胆汁淤积性肝病和胆固醇性胆结石。它通过改善胆汁流动性、保护肝细胞和降低胆

CATO标准品专业提供熊去氧胆酸系列的标准品

货号

中文名

英文名

CAS

C4X-142238

牛磺胆酸-d5钠盐

Taurocholic Acid-d5 Sodium Salt

C4X-142261

熊去氧胆酸杂质61

Ursodeoxycholic acid impurity 61

110107-03-4

C4X-142262

熊去氧胆酸杂质62

Ursodeoxycholic acid impurity 62

C4X-142268

熊去氧胆酸杂质68

Ursodeoxycholic Acid Impurity 68

C4X-142254

熊去氧胆酸杂质54

Ursodeoxycholic acid impurity 54

57011-24-2

C4X-142235

熊去氧胆酸-d5

Ursodeoxycholic Acid-d5

93701-18-9

C4X-142227

熊去氧胆酸杂质27

Ursodeoxycholic acid impurity 27

77059-13-3

C4X-142234

别鹅去氧胆酸

Allochenodeoxycholic acid

15357-34-3

C4X-142265

熊去氧胆酸杂质65

Ursodeoxycholic Acid Impurity 65

C4X-142266

熊去氧胆酸杂质66

Ursodeoxycholic Acid Impurity 66

C4X-142233

甘氨鹅脱氧胆酸乙酯

Glycochenodeoxycholic Acid Ethyl Ester

70779-05-4

C4X-142249

熊去氧胆酸杂质49

Ursodeoxycholic acid impurity 49

347841-46-7

C4X-142255

熊去氧胆酸杂质55

Ursodeoxycholic acid impurity 55

C4X-142269

熊去氧胆酸杂质69

Ursodeoxycholic Acid Impurity 69

C4X-1422

熊去氧胆酸

Ursodeoxycholic acid

128-13-2

C4X-14221

熊去氧胆酸EP杂质F

Ursodeoxycholic Acid EP Impurity F

4651-67-6

C4X-142210

熊去氧胆酸EP杂质I

Ursodeoxycholic Acid EP Impurity I

130593-75-8

C4X-142212

熊去氧胆酸杂质12

Ursodeoxycholic Impurity 12

16409-34-0

C4X-142214

熊去氧胆酸杂质14

Ursodeoxycholic Impurity 14

345909-26-4

C4X-142215

熊去氧胆酸杂质15

Ursodeoxycholic Impurity 15

6009-98-9

C4X-142217

熊去氧胆酸杂质17

Ursodeoxycholic Impurity 17

6042-32-6

C4X-142218

熊去氧胆酸杂质18

Ursodeoxycholic Impurity 18

1192657-83-2

C4X-14222

熊去氧胆酸杂质2(甘氨熊去氧胆酸)

Ursodeoxycholic Acid Impurity 2(Glycoursodeoxycholic Acid)

64480-66-6

C4X-142221

牛磺鹅去氧胆酸

Taurochenodeoxycholic Acid

516-35-8

C4X-142222

熊去氧胆酸杂质22

Ursodeoxycholic Acid Impurity 22

566-24-5

C4X-142223

熊去氧胆酸杂质23

Ursodeoxycholic acid Impurity 23

C4X-142224

熊去氧胆酸杂质24

Ursodeoxycholic acid impurity 24

640-79-9

C4X-142225

熊去氧胆酸杂质25

Ursodeoxycholic acid impurity 25

4185-00-6

C4X-142226

熊去氧胆酸杂质26

Ursodeoxycholic acid impurity 26

859-97-2

C4X-142228

熊去氧胆酸杂质28

Ursodeoxycholic acid impurity 28

1553-56-6

C4X-142229

熊去氧胆酸杂质29

Ursodeoxycholic acid impurity 29

C4X-142230

熊去氧胆酸杂质30

Ursodeoxycholic acid impurity 30

668-49-5

C4X-14223

熊去氧胆酸EP杂质A

Ursodeoxycholic Acid EP Impurity A

474-25-9

C4X-142231

熊去氧胆酸杂质31

Ursodeoxycholic acid impurity 31

566-17-6

C4X-142232

甘氨胆酸乙酯

Glycocholic acid Ethyl ester

517904-33-5

C4X-142236

牛磺熊脱氧胆酸-2,2,3,4,4-d5

Tauroursodeoxycholic-2,2,3,4,4-d5 Acid

1207294-25-4

C4X-142237

牛磺鹅去氧胆酸钠-d5 钠盐

Taurochenodeoxycholic Acid-d5 Sodium Salt

C4X-142239

甘胺熊去氧胆酸-d5

Glycoursodeoxycholic Acid-d5

C4X-14224

熊去氧胆酸EP杂质C

Ursodeoxycholic Acid EP Impurity C

434-13-9

C4X-142240

鹅脱氧胆酸甲酯

Chenodeoxycholic acid methyl

3057-04-3

C4X-142241

牛磺胆酸-d8 钠盐

Taurocholic Acid-d8 Sodium Salt

1351996-69-4

C4X-142242

牛磺石胆酸

Taurolithocholic Acid

516-90-5

C4X-142243

熊去氧胆酸乙酯

Ethyl Ursodeoxycholate

69519-36-4

C4X-142244

牛磺去氧胆酸

Taurodeoxycholic Acid

516-50-7

C4X-142245

3α-羟基-7-oxo胆酰牛磺酸

3α-Hydroxy-7-oxocholanoyltaurine

75808-01-4

C4X-142246

牛磺熊胆酸

Taurourscholic acid

86386-60-9

C4X-142247

熊去氧胆酸杂质27

Ursodeoxycholic acid impurity 27

77060-26-5

C4X-142248

牛磺脱氧胆酸

Tauroursodeoxycholic Acid

14605-22-2

C4X-14225

熊去氧胆酸EP杂质B

Ursodeoxycholic Acid EP Impurity B

81-25-4

C4X-142250

熊去氧胆酸杂质50

Ursodeoxycholic acid impurity 50

2044276-17-5

C4X-142251

3β-胆酸

3β-Cholic Acid

3338-16-7

C4X-142252

熊去氧胆酸杂质52

Ursodeoxycholic acid impurity 52

517-37-3

C4X-142253

异异石胆酸

Isoallolithocholic Acid

2276-93-9

C4X-142256

熊去氧胆酸杂质56

Ursodeoxycholic acid impurity 56

15073-99-1

C4X-142257

乙醇酸胆酸乙酯

Ethyl Glycodeoxycholate

70779-06-5

C4X-142258

胆酸杂质58

Cholic Acid Impurity 58

105227-28-9

C4X-142259

熊去氧胆酸杂质59

Ursodeoxycholic Acid Impurity 59

338950-81-5

C4X-14226

熊去氧胆酸EP杂质D

Ursodeoxycholic Acid EP Impurity D

2955-27-3

C4X-142260

牛磺脱氧胆酸-D4 (non-labelled)

Tauroursodeoxycholic-d4 Acid (Tauroursodiol-d4)

14605-22-2

C4X-142263

熊去氧胆酸杂质63

Ursodeoxycholic acid impurity 63

81873-91-8

C4X-142267

甘氨石胆酸3-磺酸二钠盐

3-Sulfoglycolithocholic Acid Disodium Salt

64936-82-9

C4X-14227

熊去氧胆酸EP杂质E

Ursodeoxycholic Acid EP Impurity E

83-44-3

C4X-142270

熊去氧胆酸杂质70

Ursodeoxycholic Acid Impurity 70

C4X-142272

熊去氧胆酸杂质72

Ursodeoxycholic Acid impurity 72

C4X-142271

熊去氧胆酸杂质71

Ursodeoxycholic Acid Impurity 71

C4X-14229

熊去氧胆酸EP杂质H

Ursodeoxycholic Acid EP Impurity H

78919-26-3

C4X-14228

熊去氧胆酸EP杂质G

Ursodeoxycholic Acid EP Impurity G

10538-55-3

广州佳途科技股份有限公司，CATO标准品厂家，提供熊去氧胆酸全套杂质，严格的控制质量，通过全面检测，高效沟通，专业服务，完善的售后，所有产品均能现货供应。